Citrulline Malate is an amino acid with the main benefits of muscle growth, sustained muscle protein synthesis, and post-training recovery. All of these benefits are attributed to elevated blood arginine levels which have lead to greater Nitric Oxide (NO) production, muscle protein synthesis, and faster recovery. The process in which Citrulline is effective for reducing fatigue during training comes from the exchange typically produced. Citrulline is produced when Ornithine combines with Carbamoyl Phosphate, which occurs during the urea cycle when your body removes nitrogen waste. The addition of supplementing Citrulline in the body is said to put the urea cycle in overdrive, allowing it to suck up more ammonia (composed of nitrogen molecules) which are produced by working muscles. This in combination reduces the fatigue caused by muscles at the source.
The excess of Citrulline triggers a stronger effect of arginine conversion into nitric oxide (NO). The increase in arginine in the blood leads to increased NO production, the increase of NO increases blood flow during exercise and allows for muscles to perform for longer while under duress, which gives weightlifters the ability to produce bigger muscle pumps. The combined form of Citrulline with Malate has a second added effect to reducing fatigue, the malate helps the body recycle lactic acid and use it for energy. The end result of increased ammonia removal, lactic acid recycling and postponing the decrease in muscle pH levels allows users to have increased repetition count. Another study confirmed the increase in repetition but it has also found that it delayed the body's immunosuppressive mechanics when performing intense exercise. This means it can potentially help the body heal from intense training and avoid some of the symptoms associated with "overtraining".
The mechanisms of Citrulline during exercise has more uses other than just increasing blood arginine levels, it has a wide range of benefits including elevated protein synthesis, creatine synthesis, and more effective BCAA utilitization by muscles during exercise. Supplementing with Citrulline Malate has been growing in practice over the use of Arginine as studies have shown that Citrulline is more effective at increasing plasma arginine levels in the body. A recent study has shown that 3 grams of Citrulline Malate improves vascular function and vasodilation equivalent to 6 grams of arginine. This translates to more effective supplementation with lower intake values. Arginine has been known to cause upset stomach or digestive irritation due to the higher dosage while these same side-effects are far less common when supplementing with Citrulline.
Directions & Allergens
As a dietary supplement, take 3000 mg (~1/2 tbsp) twice daily with 16 ounces of water or suitable beverage. Taken 30 minutes prior to workout and again immediately after for maximum results.
This product contains no Soy, Dairy, Dairy byproducts, Eggs, Fish, Shellfish, Wheat, Gluten, Tree Nuts, or Sesame Seeds.
This is a NON-GMO ingredient manufactured using organic starting ingredients.
Store in a cool, dry place. Re-seal zipper immediately after use to preserve freshness.
Statements & Warnings
† These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.
Keep out of the reach of children. Do not take this or any other supplement if under the age of 18, pregnant or nursing a baby, or if you have any known or suspected medical conditions and/or taking prescription drug(s) or OTC medication(s). Always consult with a qualified health physician before taking any new dietary supplement.
Noticed a significant increase in "Pump" during a hard work out and provided an extra endurance threshold.
Pleased with this new found product.
vey good product
I started taking L-Citrulline after reading an article on climbing.com about how it helped an average climber move up into more intermediate grades by allowing him to recover faster, spend more time on the wall by increasing his endurance (reps essentially) and helped him avoid overtraining. I noticed all of the above almost immediately and have been taking it for close to a year now with a small break in between - only because I ran out. I also happen to know that Eric Horst, who is one of the most elite climbing coaches takes L-Citrulline daily for recovery. He told me this in person and was impressed that as a young climber I had stumbled across this supplement so early in my career. This is the single most effective supplement for climbers. Highly recommend it.
I use the product for running. My legs don't get as fatigued as they did before use citrulline malate. I used beet juice powDer before but the taste was awful. Citrulline malate doesn't taste bad at all. I totally recommend it if you want to improve your running stamina.